歯周炎患者の全唾液中thiolと揮発性硫化物について
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This investigation were performed to evaluate the relationship among thiol in incubated whole saliva and volatile sulphur compounds from incubated whole saliva and mouth air in three subjects groups. The subjects were divided into three groups based on clinical findings and intensity of odour by olfactory panel of trained judges, Group N: normal subjects, Group P-N: Periodontal patients without halitotis, Group P-H: periodontal patients with halitotis. Volatile sulphur compounds from incubated whole saliva and mouth air were determined by gas chromatograph equipped with flame photometric detector and thiol in the supernatant of incubated whole saliva were determined by spectrophotometer. Result were as flowed. 1) In periodotal patients, thiol in supernatant was detected prior to CH_3 SH from incubated whole saliva, although they increased with time thereafter, there was 12〜18 hours' difference in the time of their reaching their maximun quantity. 2) The thiol in the supernatant of incubated whole saliva and the methyl marcaptan produced from whole saliva from periodotal patients were of greater quantity than those from the normal. Furthermore Group P-H produced remarkably greater amount of thiol and methyl mercaptan than Group P-N. Also, in Group P-H a close correlation was confirmed between the highest values of the quantities of thiol and methyl mercaptan produced from incubated whole saliva. 3) Obvious correlationship was observed between the methyl mercaptan content in mouth air and the highest values of that produced from the incubated whole saliva. 4) In the periodotal patients, whereas no correlation was observed between the quantity of metyl mercaptan produced from the incubated whole saliva and P.I., there were a slight the correlation between pocket depth or bleeding and that, and a close correlation of that between discharge of pus and that. However, it was difficult to determine the correlation with G.I. coefficients being r=0.51.
- 特定非営利活動法人日本歯周病学会の論文
- 1980-06-28
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