Ethanol Similarly Induces Ascorbic Acid Release in the Prefrontal Cortex and Striatum of Freely Moving Mice

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概要

• 論文の詳細を見る

• Previous studies have shown that acute systemic administration of ethanol induced striatal ascorbic acid (AA) release in mice and rats. Undercutting the prefrontal cortex completely eliminated ethanol-induced AA release in rat striatum. In the present study, in vivo brain dialysis coupled with high performance liquid chromatography (HPLC)-electrochemical detection was used to evaluate the effect of ethanol on the release of AA in the prefrontal cortex, compared to that in the striatum of freely moving mice. The results showed that ethanol (4.0g/kg i.p.) similarly induced AA release in the prefrontal cortex and striatum of freely moving mice.

• 公益社団法人日本薬学会の論文
• 2006-08-01

著者

• Guo Tao

  General Hospital Of Shenyang Military Region

• Hou Yue

  Shenyang Pharmaceutical University:general Hospital Of Shenyang Military Region

• WU Chunfu

  Shenyang Pharmaceutical University

• HE Xiang

  General Hospital of Shenyang Military Region

• HOU Yue

  General Hospital of Shenyang Military Region

• YANG Jingyu

  Shenyang Pharmaceutical University

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• Ethanol Similarly Induces Ascorbic Acid Release in the Prefrontal Cortex and Striatum of Freely Moving Mice

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