Tissue-Engineered Odontogenesis(International Symposium of Maxillofacial and Oral Regenerative Biology in Okayama 2005)
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概要
- 論文の詳細を見る
In this study, we have developed a tooth regeneration model derived from mouse tooth germ cells based on tissue engineering. Lower first molars from DDY mice embryos at E 14 were used. Biodegradable Polyglycolate acid (PGA) scaffolds were fabricated, seeded with dissociated the first molars cells, and implanted into the subcapsular layer of kidney in an adult mouse where they allowed to develop over 3, 5, 7, and 14 days. We present histological analyses characterizing tissue-engineered tooth (TE-tooth). Histological analysis of 14 day implants tissue revealed mineralized enamel and dentin layer were apparent, of the kind of found in normally developing teeth.
- 硬組織再生生物学会の論文
著者
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HARADA Hidemitsu
Department of Oral Anatomy and Cell Biology, Kyushu Dental College
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HONDA Masaki
Tooth Regeneration, Division of Stem Cell Engineering, The Institute of Medical Science, The Univers
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UEDA Minoru
Tooth Regeneration, Division of Stem Cell Engineering, The Institute of Medical Science, The Univers
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IWATSUKI Shinji
Tooth Regeneration, Division of Stem Cell Engineering, Institute of Medical Science, University of T
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Iwatsuki Shinji
Tooth Regeneration Division Of Stem Cell Engineering Institute Of Medical Science University Of Toky
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Iwatsuki Shinji
Tooth Regeneration Division Of Stem Cell Engineering The Institute Of Medical Science The University
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Honda Masaki
Tooth Regeneration Division Of Stem Cell Engineering The Institute Of Medical Science The University
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Harada Hidemitsu
Department Of Anatomy And Developmental Biology Osaka University Graduate School Of Dentistry
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Ueda Minoru
Tooth Regeneration Division Of Stem Cell Engineering The Institute Of Medical Science The University Of Tokyo:department Of Oral And Maxillofacial Surgery Nagoya University Graduate School Of Medicine
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