Plain Computed Tomography for Assessment of Early Coronary Microcirculatory Damage After Revascularization Therapy in Acute Myocardial Infarction
スポンサーリンク
概要
- 論文の詳細を見る
Background Coronary microcirculatory damage is an important factor for the prognosis for acute myocardial infarction (MI) after revascularization. The myocardial enhancement area with contrast media infused during coronary revascularization therapy, detected by computed tomography (CT) just after revascularization, has been reported to correspond to the area of hemorrhagic infarction. The relationship between myocardial contrast enhancement and coronary microcirculatory damage was investigated in the present study. Methods and Results Thirteen patients with acute anterior MI underwent successful coronary revascularization within 6h of symptom onset were enrolled. The coronary flow velocity pattern was measured using a Doppler guidewire and chest CT assessments were performed immediately after coronary revascularization. The ratio of mean CT number of the highest-enhanced myocardial area and the lumen of the left ventricle was defined as a relative CT number. The relative CT number significantly correlated with coronary diastolic deceleration time (r=-0.78, p<0.002) and coronary diastolic deceleration rate (r=0.74, p<0.04). It also correlated with peak myocardial enzyme release in plasma. Conclusion Myocardial contrast enhancement detected using plain CT just after coronary reperfusion therapy implies coronary microcirculatory damage in acute ML The relative CT number is useful in evaluating the impaired coronary microcirculatory state.
- 社団法人日本循環器学会の論文
- 2006-10-20
著者
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Habara Seiji
Department of Cardiology, Kurashiki Central Hospital
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Hasegawa Daiji
Department of Cardiology, Kurashiki Central Hospital
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KATO Masaya
Department of Physics,Division of Material Science,Nagoya University
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Kato Masaya
Department Of Cardiology Hiroshima City Asa Hospital
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Dote Keigo
Department of Cardiology, Hiroshima City, Asa Hospital
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Sasaki Shota
Department of Cardiology, Hiroshima City, Asa Hospital
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Ueda Kentaro
Department of Cardiology, Hiroshima City, Asa Hospital
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Matsuda Osamu
Department of Cardiology, Toyohashi heart center
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Nakano Yoshinori
Department of cardiology, Hiroshima Cuty Asa Hospital
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Takemoto Hiroaki
Department of Medicine and Molecular Science, Graduate School of Biomedical Sciences, Hiroshima Univ
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Dote Keigo
Department Of Cardiology Hiroshima City Asa Hospital
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Ueda Kentaro
Department Of Cardiology Hiroshima City Asa Hospital
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Sasaki Shota
Department Of Cardiology Hiroshima City Asa Hospital
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Naganuma Toru
Department Of Cardiology Hiroshima City Asa Hospital
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Goto Kenji
Department Of Cardiology Matsue Red Cross Hospital
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Gotoh Kenji
Department Of Cardiology Hiroshima City Asa Hospital
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Habara Seiji
Department Of Cardiology Hiroshima City Asa Hospital
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Hasegawa Daiji
Department Of Cardiology Hiroshima City Asa Hospital
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Matuda Osamu
Department of Cardiology, Hiroshima City Asa Hospital
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Matuda Osamu
Department Of Cardiology Hiroshima City Asa Hospital
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Dote Keigo
Department Of Cardiology Hiroshima-city Asa Hospital
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Nakano Yoshinori
Department Of Cardiology Hiroshima City Asa Hospital
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Takemoto Hiroaki
Department Of Cardiology Hiroshima City Asa Hospital
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Takemoto Hiroaki
Department Of Cardiology Hiroshima-city Asa Hospital
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Dote Keigo
Department Of Cardiovascular Medicine Asa-city Hospital
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Goto Kenji
Department Of Anesthesiology And Resuscitology Okayama University Medical School
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Matsuda Osamu
Department Of Applied Physics Faculty Of Engineering Hokkaido University
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