Solubility Prediction of Paracetamol in Binary and Ternary Solvent Mixtures Using Jouyban-Acree Model
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概要
- 論文の詳細を見る
The Jouyban-Acree model has been used to predict the solubility of paracetamol in water-ethanol-propylene glycol binary and ternary mixtures based on model constants computed using a minimum number of solubility data of the solute in water-ethanol, water-propylene glycol and ethanol-propylene glycol binary mixtures. Three data points from each binary solvent system and solubilities in neat solvents were used to calculate the binary interaction parameters of the model. Then the solubility at other binary solvent compositions as well as in a number of ternary solvents were predicted, and the mean percentage deviation (±S.D.) of predicted values from experimental solubilities was 7.4(±6.1)%.
- 社団法人日本薬学会の論文
- 2006-04-01
著者
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Chan H‐k
Faculty Of Pharmacy The University Of Sydney
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JOUYBAN Abolghasem
Faculty of Pharmacy and Drug Applied Research Center, Tabriz University of Medical Sciences
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CHAN Hak-Kim
Faculty of Pharmacy, The University of Sydney
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CHEW Nora
Faculty of Pharmacy, The University of Sydney
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KHOUBNASABJAFARI Maryam
Kimia Research Institute
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ACREE William
Department of Chemistry, University of North Texas
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Acree W
Department Of Chemistry University Of North Texas
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Jouyban Abolghasem
Faculty Of Pharmacy And Drug Applied Research Center Tabriz University Of Medical Sciences
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Chan Hak-kim
Faculty Of Pharmacy The University Of Sydney
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Chew Nora
Faculty Of Pharmacy The University Of Sydney
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Acree William
Department Of Chemistry University Of North Texas
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Jouyban A
Faculty Of Pharmacy And Drug Applied Research Center Tabriz University Of Medical Sciences
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Jouyban Abolghasem
Faculty Of Pharmacy And Drug Applied Research Centre Tabriz University Of Medical Sciences
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Jouyban Abolghasem
Fac. Of Pharmacy And Drug Applied Res. Center Tabriz Univ. Of Medical Sciences
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