虚血性心疾患における運動負荷心プールシンチグラフィーの臨床的評価 : 特に位相解析法の臨床的有用性について
スポンサーリンク
概要
- 論文の詳細を見る
The present study was undertaken to evaluate the clinical usefulness of exercise equilibrium radionuclide angiography (RI angio) in patients with ischemic heart disease (IHD), especially, for assessing the severity of exercise-induced ischemia. Fifteen patients (pts) with effort angina pectoris (EAP), 20pts with old myocardial infarction (OMI) and 8 normal subjects underwent exercise RI angio, TI-201 stress myocardial scintigraphy, hemodynamic monitoring during exercise, coronary angiography and left ventriculography. Results were as follows ; (1) Pts with OMI with exercise-induced left ventricular dysfunction (PAWP during exercise ≧25mmHg) showed lower resting ejection fraction (EF) and higher resting standard deviaton (SD), obtained from the histogram of the phase analysis of RI angio. (2) During exercise, EF decreased in 11pts(73%) with EAP and in 4pts(20%) with OMI, while SD increased in 14pts(93%) with EAP and in 2pts(10%) with OMI. From the above findings, SD is a more sensitive and specific index for detecting exercise-induced ischemia than EF. (3) Changes in SD during exercise closely correlated with maximum work load (≧100W 11.4±5.46°v.s.<100W 18.7±6.25, p<0.05), number of involved vessels (single vessel 12.7±4.69°vs multi vessel 21.2±6.31°, P<0.01), PAWP during exercise (≧25mmHg 19.7±5.83° vs<25mmHg 8.33±3.51°, p<0.05) and the difference between thallium score at maximum exercise and that in delayed image 2.5 hours later (Δdefect score; γ=0.55, p<0.05). In conclusion, phase analysis of exercise RI angio is a usefull noninvasive method for assessing the severity of IHD.
- 神戸大学の論文
著者
関連論文
- Dipyridamole負荷^Tl心筋SPECTを用いた拡張型心筋症(DCM)の病態評価
- 一枝病変心筋梗塞症における運動負荷中血行動態の推移
- 虚血性心疾患における運動負荷心プールシンチグラフィーの臨床的評価 : 特に位相解析法の臨床的有用性について
- 血圧上昇発作時に一過性高アミラーゼ血症を来した褐色細胞腫の1例