Dynamic Seeding and Perfusion Culture of Hepatocytes with Galactosylated Vegetable Sponge in Packed-Bed Bioreactor(CELL AND TISSUE ENGINEERING)

スポンサーリンク

概要

• 論文の詳細を見る

• A galactose moiety was introduced into the fiber surface of a vegetable sponge by the covalent binding of lactobionic acid. The galactosylated sponge was used as scaffold for the culture of rat hepatocytes in a packed-bed bioreactor. Hepatocytes could be dynamically seeded into and uniformly distributed throughout the scaffold, and the immobilized cells maintained high albumin and urea production rates during long-term perfusion culture. The hepatocytes showed an increasing albumin production rate from 49 to 109μg/10^6 cells/d over the 7-d culture.

• 公益社団法人日本生物工学会の論文
• 2006-07-25

著者

• Chen Jyh-ping

  Graduate Institute Of Biochemical And Biomedical Engineering Chang Gung University

• Lin Chia-Tseng

  Graduate Institute of Biochemical and Biomedical Engineering, Chang Gung University

• Lin Chia-tseng

  Graduate Institute Of Biochemical And Biomedical Engineering Chang Gung University

関連論文

• Characterization and Evaluation of Silk Protein Hydrogels for Drug Delivery
• Dynamic Seeding and Perfusion Culture of Hepatocytes with Galactosylated Vegetable Sponge in Packed-Bed Bioreactor(CELL AND TISSUE ENGINEERING)

スポンサーリンク