Stability of Benzoyl Peroxide in Methyl Alcohol

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概要

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• The purpose of this study was to clarify the stability of benzoyl peroxide (BPO) in some solvents. BPO was dissolved in acetone, acetonitrile (AcCN), 50% acetonitrile-50% distilled water (50% AcCN), ethyl alcohol (EtOH), and methyl alcohol (MeOH). Solutions containing BPO were incubated for eight days at 25℃. In MeOH, BPO rapidly decomposed into benzoic acid (BA) and methyl benzoate (MeBA) time-dependently, whereas BPO in acetone, AcCN, and 50% AcCN was relatively stable. Although BPO in EtOH was slightly stable within the first 24 hours, it decomposed time-dependently such that BA and EtBA as decomposition products of BPO were produced. These results indicated that the stability of BPO in a solution was dependent on the solvent and the decomposition rate of BPO dissolved in MeOH was the fastest. These suggest that BPO can decompose even in lower-than-activation temperature by the solvent to use for its dissolution.

著者

• HONGO Toshio

  Department of Hard Tissue Engineering, Division of Bio-Matrix, Graduate School, Tokyo Medical and De

• HIKAGE Sakari

  Department of Fixed Prosthodontics, School of Dentistry, Health Sciences University of Hokkaido

• SATO Atsushige

  Department of Oral Biomaterials and Technology, Showa University School of Dentistry

• Hikage Sakari

  Department Of Fixed Prosthodontics School Of Dentistry Health Sciences University Of Hokkaido

• Hongo Toshio

  Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences University Of Tokyo

• Sato Atsushige

  Department Of Biomaterials Science Tokyo Medical & Dental University

• Hongo Toshio

  Department Of Hard Tissue Engineering Division Of Bio-matrix Graduate School Tokyo Medical And Denta

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