Ameliorating Effects of Conventional Therapy on Declining Renal Function in Patients with Diabetic Nephropathy

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概要

• 論文の詳細を見る

• The beneficial effects of conventional long treatment on declining renal function in diabetic nephropathy (non-insulin-dependent diabetes mellitus, NIDDM) were evaluated retrospectively. One hundred NIDDM patients with overt proteinuria were followed for more than three years. Clinical data before and after various regimens of treatment were compared statistically. Treatment included a calcium antagonist (CaA), alpha-methyl dopa (AMD), an alpha-blocker (ABL), angiotensin converting enzyme inhibitor (ACEI), anti-platelet agents (APL), essential amino acids (EAA), and an oral absorbent (AST-120). Changes in renal function were analyzed by comparing the degree of slopes of regression rate of the reciprocals of serum creatinine levels (Rl/Cr). Administration of ACEI and EAA resulted in Rl/Cr improvement after the initiation of treatment (p<0.05). It appears that the administration of EAA and ACEI are beneficial with regard to protection against renal failure in NIDDM patients with diabetic nephropathy.

• 東海大学の論文

著者

• Machimura Hideo

  Division Of Nephrology And Metabolism Department Of Internal Medicine Tokai University School Of Med

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• Ameliorating Effects of Conventional Therapy on Declining Renal Function in Patients with Diabetic Nephropathy

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