Transformation of Human Colostrum Lymphocytes with Epstein-Barr Virus and the Production of IgA in Culture
スポンサーリンク
概要
- 論文の詳細を見る
Human colostrum lymphocytes obtained on day 2-5 after delivery were found to be as susceptible to transformation with Epstein-Barr virus (EBV) as peripheral lymphocytes. An enzymelinked immunosorbent assay showed that the proportion of transformed cells producing IgA, IgG, and IgM varied from colostrum specimen to specimen. 1μg/ml of IgA could be produced by freshly transformed cell mixture. But the capacity to produce IgA was lost or decreased by one order of magnitude during and after cloning of producing cells; the highest production with cloned cell cultures was about 0.2μg/ml. Immunofluorescence staining of IgA-positive cells showed instability of the capacity of transformed cells to produce IgA.
- 東海大学の論文
著者
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Watanabe Yasushi
Department of Internal Cardiology, Hitachi General Hospital
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TANAKA Shigeaki
Department of Applied Chemistry, Faculty of Engineering, Osaka City University
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Watanabe Y
Department Of Molecular Life Science 2 School Of Medicine Tokai University
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TAKEKOSHI Masataka
Department of Molecular Life Science 2, Tokai University School of Medicine
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Takekoshi Masataka
Department Of Molecular Life Science 2 School Of Medicine Tokai University
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MAEDA-TAKEKOSHI Fumiko
Department of Molecular Life Science 2, School of Medicine, Tokai University
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KIKUCHI Eiichi
Technical Research Institute, Snow Brand Milk Products Co., Ltd.
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Kikuchi E
Tokyo Metropolitan Coll. Allied Medical Sci. Tokyo Jpn
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Maeda-takekoshi Fumiko
Department Of Molecular Life Science 2 School Of Medicine Tokai University
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Tanaka Shigeaki
Department Of Applied Chemistry Faculty Of Engineering Osaka City University
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Kikuchi Eiichi
Technical Research Institute Snow Brand Milk Products Co. Ltd.
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Dosako Shun'ichi
Technical Research Institute Snow Brand Milk Products Co. Ltd.
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Watanabe Yasushi
Department Of Agricultural Chemistry Faculty Of Agriculture Shizuoka University
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