出雲市の青年女子における風疹抗体保有状況と弱毒風疹生ワクチン(高橋株)の野外接種試験

概要

論文の詳細を見る
In July 1972, a rubella serological surveillance was performed 383 students aged 15 to 18 in Izumo High School girls and 83 students aged 15 to 17 in Izumo Nurses' Training School in Izumo city. Among these, seronegative students were immunized with live attenuated rubella vaccine, Takahashi strain. In the serological survey, 297 out of 383 students (77.5%) in the high school girls and 62 out of 83 students (74.6%) in the nurses' training school were seronegative (< 1:8) by the hemagglutination-inhibition (HI) test. In the immunization with rubella vaccine, the vaccine was given to a total of 334 seronegative students in two schools, all of whom demonstrated rubella HI antibody production. The vaccine caused no clinical reactions, such as fever, rash, lymphadenopathy or arthritis. One year after immunization with rubella vaccine, 35 nurses' training school students were determined to have a persistence of vaccine-induced HI antibody. Antibody titers were very well maintained.
北里大学の論文
1976-04-30