Part 2) Clinical Application of Nerve Conduits Consisting of a Polyglycolic Acid (PGA)-Collagen Composite Tube Filled with Collagen Sponge(<Special Issue>Roles of Extracellular Matrix in the Development and Regeneration of Nervous Systems)
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概要
- 論文の詳細を見る
Clinical application of bioabsorbable nerve conduits began on 1st February 2002, in Japan. A total of 65 grafts were inserted in 46 patients in four hospitals until the 31th October 2002. Each conduit consisted of a polyglycolic acid tube coated with collagen and filled with collagen sponge. The conduits ranged from 0.7-13 mm in diameter and 4-94 mm in length. Indications included peripheral nerve injury, mainly common and proper digital nerves, and neural invasion by tumors. To date, no side-effects or complications have been reported in any of the treated patients. Rapid recovery of nerve function was observed in several patients. Such conduits are promising for clinical use as an alternative to conventional autografts.
- 日本結合組織学会の論文
- 2003-03-25
著者
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Nakamura Tatsuo
Department Of Artificial Organs Institute For Frontier Medical Sciences Kyoto University
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Nakamura Tatsuo
京都大学再生医科学研究所
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- Part 2) Clinical Application of Nerve Conduits Consisting of a Polyglycolic Acid (PGA)-Collagen Composite Tube Filled with Collagen Sponge(Roles of Extracellular Matrix in the Development and Regeneration of Nervous Systems)