Structural Studies on Phosphatidylcholine Liposomes in Various Phases Using Atomic Force Microscopy (<Special Issue> Scanning Tunneling Microscopy)

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概要

• 論文の詳細を見る

• Structural studies on phosphatidylcholine liposomes in various phases were carried out using atomic force microscopy (AFM) by applying a newly proposed fixation method under aqueous conditions. With soybean lecithin liposomes in air at room temperature (liquid crystalline phase), only irregular images were observed under magnification. On the other hand, with dipalmitoylphosphatidylcholine (DPPC) liposomes in air at room temperature (gel phase), regular two-dimensional molecular arrays were observed. With dimyristoylphosphatidylcholine (DMPC) liposomes in water at 18℃ (sub-gel phase) on mica substrates immobilized by centrifugation, various types of ripple structures were seen. It was shown that our fixation method using centrifugation is suitable for the AFM observation of artificial membranes under aqueous conditions.

• 社団法人応用物理学会の論文
• 1997-06-30

著者

• Iwamoto Hideki

  Department Of Materials Science And Technology Faculty Of Engineering Toin University Of Yokohama

• WAKAYAMA Nobuyuki

  Department of Materials Science and Technology, Faculty of Engineering, Toin University of Yokohama

• Wakayama Nobuyuki

  Department Of Materials Science And Technology Faculty Of Engineering Toin University Of Yokohama

関連論文

• Structural Studies on Phosphatidylcholine Liposomes in Various Phases Using Atomic Force Microscopy ( Scanning Tunneling Microscopy)
• Atomic force microscopy in structural biology : from the subcellular to the submolecular
• Atomic Force Microscopy Studies of Erythocyte Membranes Immobilized by Centrifugation under Aqueous Conditions ( Scanning Tunneling Microscopy)

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