歯肉溝浸出液のタンパク分画の分析 : その特徴と歯周疾患における変動

概要

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We have been studied the characteristics of protein components in gingival crevicular fluid (GCF) with isoelectric focusing technique. The purpose of this study was to investigate the relationship between those proteins and clinical findings such as Gingival Index (Loe & Sillness), Pocket depth, Plaque Index (Quigley & Hein), Gingival Bleeding Index and Bone Index. GCF, serum and mixed saliva collected from the same subject were analyzed, and following results were obtained. The patterns of protein bands in GCF were similar to those in serum but different from mixed saliva, and the pI of main protein band of GCF and serum were 4.9. No apparent difference was observed on the patterns between clinicaly healthy gingiva and those receivecl reriodontal disease. Protein patterns were compared with the before mentioned clinical findings and GCF volume. Main protein bands were observed on cathode side (pI 8.0-9.0) at the patterns against Gingival Index : 0-1 or >2, Gingival Bleeding Index : + or -, Pocket Depth : 0-l or >2 and Bone Index : 1 or >3. It was suggested that the study of the proteins on cathode side is important.
日本補綴歯科学会の論文
1990-04-01