職業癌研究の方法論

概要

論文の詳細を見る
Recent development of the methodology of occupational cancer research was reviewed, in regard to the experimental and epidemiological approach. The author's attention was directed toward the evaluation of the results of animal experiment, particularly toward the standardization of carcinogenic potency, presented by Horton and Denman. Concerning the epidemiological methods, a paper prepared by the Committee on Occupational Cancer of Council of Industrial Health, U.S.A. 1948 was chiefly introduced. A result obtained by the present author was also quoted, comparing the date which showed about a double high "relative frequency" of lung cancer among workers in chromium and nicickel industries in comparison with the expected, to the other which resulted in the same conclusion by means of the computation of age adjusted death rates from the same material. In the latter, the observed lung cancer deaths were compared to the expected, calculated from the population record in the same year, and showed again significantly a higher figure (p=0.01) in the above mentioned industries. The result implies that the "relative frequency" would be useful when the denominator for computing a death rate is not available, although there are some limitations. Biochemical studies on the induction of the bladder cancer, developed by Bonser, Boyland and others were discussed, with ultimate hope that ideas akin to this in the study of occupational cancer would lead to the elucidation of other "natural cancers" among human beings. Finally the author did not forget to add that studies in this field be much more vigorously promoted in this country in light of rapid development of industrialization.
社団法人日本産業衛生学会の論文

職業癌研究の方法論

スポンサーリンク

概要

著者

関連論文

スポンサーリンク