Neuroleptic-Like Properties of the Chloroform Extract of Maytenus obtusifolia M_<ART>. Roots(Pharmacology)
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概要
- 論文の詳細を見る
The effects of the chloroform extract of Maytenus obtufisolia M_<ART>, roots on locomotor activity, catalepsy test, amphetamine-induced toxicity and active-avoidance test were studied. The results revealed that the extract caused a decrease in spontaneous activity and induced catalepsy in mice up to 240 min. The extract significantly protected the mice against amphetamine-induced toxicity and decreased the conditioned response in rats, in a dose-related manner. The results suggest that the chloroform extract of Maytenus obtusifolia M_<ART>, possesses neuroleptic-like properties.
- 公益社団法人日本薬学会の論文
- 2005-02-01
著者
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Sousa Damiao
Laboratorio De Tecnologia Farmaceutica Universidade Federal Da Paraiba
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Sousa Damiao
Laboratorio De Quimica Bio-organica Departamento De Quimica Universidade Federal De Sao Carlos
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Almeida Reinaldo
Laboratorio De Tecnologia Farmaceutica Universidade Federal Da Paraiba
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