Studies on the Synthesis of Amino Acids by the Schmidt Reaction. VI. Synthesis of Methionine Sulfoximine Analogs
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Toxic substance, which is contained in wheat flour treated with nitrogen trichloride and causing dogs to suffer a fit like epilepsy, was separated by Bently, et al. Although it had been confirmed that this substance is a specific compound having O atom and NH group attached to S atom, its analogs have not yet been synthesized. Therefore, several of its analogs were prepared by the reaction of (2-alkylthioethyl) malonic acid with hydrazoic acid.
- 公益社団法人日本薬学会の論文
- 1960-03-25
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関連論文
- Studies on the Synthesis of Amino Acids by the Schmidt Reaction. VI. Synthesis of Methionine Sulfoximine Analogs
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