An Application of Molecular Orbital Theory for Screening Research of Antifungal Drugs
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概要
- 論文の詳細を見る
The relationship between antifungal activity and the energy of the lowest unoccupied molecular orbital (LUMO) of several phenolic compounds was examined using MINDO/3 method. Among the phenols examined, all the compounds which are highly active in inhibiting the growth of fungi possess a low-lying LUMO as compared with the compounds poor in antifungal activity. From these results, it is conceivable that the LUMO energy of a molecule should be one of the useful indices for screening antifungal drugs.
- 公益社団法人日本薬学会の論文
- 1980-06-25
著者
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津田 穰
Laboratory Of Bio-physical Chemistry Faculty Of Pharmaceutical Sciences Chiba University
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笈川 節子
Laboratory of Bio-physical Chemistry, Faculty of Pharmaceutical Sciences, Chiba University
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大野木 重和
Laboratory of Physical Chemistry, Faculty of Pharmaceutical Sciences, Chiba University
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栗田 啓幸
Research Institute for Chemobiodynamics, Chiba University
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笈川 節子
千葉大学薬学部
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大野木 重和
Laboratory Of Physical Chemistry Faculty Of Pharmaceutical Sciences Chiba University
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栗田 啓幸
Research Institute For Chemobiodynamics Chiba University
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