Trimetazidine in Blood, Bile, Organs and Urine

スポンサーリンク

概要

• 論文の詳細を見る

• Plasma levels of trimetazidine in rabbits, rats, and mice were determined. Plasma levels in animals showed unusual curve about 1 hr after oral administration and this reason was investigated by determining distribution of the drug in animal tissues and excretion of the drug in bile. Metabolic pathways of trimetazidine in rabbits were investigated qualitatively and it was ascertained by thin-layer chromatography that the methylene group connecting the benzene and piperazine rings is not severed by metabolism in rabbits.

• 社団法人日本薬学会の論文
• 1972-04-25

著者

• 内藤 俊一

  Kyoto College Of Pharmacy

• 大隅 清明

  Kyoto College of Pharmacy

• 関城 暁子

  Kyoto College of Pharmacy

• 廣瀬 みち子

  Kyoto College of Pharmacy

関連論文

• Hydrolysis of Bis (p-hydroxyphenyl) pyridyl-2-methane Disulfate. I. Presence of Arylsulfatase and Laxative Activity
• Trimetazidine in Blood, Bile, Organs and Urine
• Techniques for Manufacturing Pharmacy. II. Prediction of Tableting Troubles such as Capping and Sticking. (2)
• Pharmaceutical Studies on 2-Aminoethanesulfonic Acid Derivatives. I. Aminoethanesulfonylphenetidine. (1). Stability Studies
• Pharmaceutical Studies on 2-Aminoethanesulfonic Acid Derivatives. II. 4-(Aminoethanesulfonylamino) antipyrine. (1). Stability Studies
• Studies on Techniques of Manufacturing Pharmacy. I. Prediction of Tableting Troubles such as Capping and Sticking. (I)
• Biopharmaceutical Studies on Guaiacol Glycerol Ether and Related Compounds. III. Metabolites of Guaiacol Glycerol Ether and Its Mononicotinate.
• Biopharmaceutical Studies on Guaiacol Glycerol Ether and Related Compounds. II. Hypocholesteremic Action. (1)
• Studies on Absorption and Excretion of Drugs. XXIX. Biopharmaceutical Studies on Guaiacol Glycerol Ether and Related Compounds. I. Blood Level of Guaiacol Glycerol Ether in Rabbit and Its Binding with Serum Proteins.

スポンサーリンク