有機ケイ素化合物の合成(第13報) : o-, m-およびp-(Trimethylsilyl)benzoic Acidの臭素化反応について

概要

論文の詳細を見る
Bromination of trimethylsilylbenzoic acids was examined. Addition of equimolar amount of bromine to the acetic acid solution of o-, m-, and p-(trimethylsilyl)benzoic acid, and heating of this mixture in a sealed tube at 100° for 5,12,and 13 hours respectively afforded o-, m-, and p-bromobenzoic acids. The ease or difficulty of this bromination by desilylation was found to be proportional to the activity of the ortho, meta, and para positions of the benzoic acid.
公益社団法人日本薬学会の論文
1967-05-25