紫雲膏の薬学的研究(第1報) : 紫雲膏の抗菌性について

概要

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"Shiunko"is an old Japanese medicinal prescription and is an effective purple ointment from Lithospermi (or Macrotomiae) Radix, Angelicae Radix, Oleum Sesami, Cera Flava, and Adeps Suillus. This ointment have been used for suppurative skin diseases such as eczema, haemorrhoids, pimple, dermatophytosis, callus. Antibacterial substances in"Shiunko"were found to be coloring compounds contained in"Nanshikon" (a kind of Shikon). These compounds were extracted and isolated. Five naphthoquinone derivatives, β, β-dimethylacryl-shikonin (II), acetyl-shikonin (III), teracryl-shikonin (IV), shikonin (V), and β-hydroxyisovaleryl-shikonin (VI) were obtained and their antibacterial action tested. All the pigments inhibited the growth of Bacillus subtilis, Staphylococcus aureus, and Sarcina lutea, but not that of Escherichia coli.
社団法人日本薬学会の論文
1972-05-25