天然物, カルバニオン, チアゾリンそしてβ-ラクタムの化学

概要

論文の詳細を見る
This article describes the works of one of Tsuda's students who owes their performance to him through the longterm, direct and indirect influence of the Tsuda school, especially supervised by him during his very last period as a Professor at the University of Tokyo. They consist of i) natural product chemistry, i.e. Siccanin and related congeners, ii) carbanion chemistry, i.e. iodomethylation (C1) and trans-iodopropenylation (C3) reactions using thiazoline derivatives and their synthetic application, and iii) β-lactam chemistry, i.e. 1,3-dipoler cycloaddition reaction of iminochloride of penicillin, new β-lactam ring synthesis, synthesis of carbapenem derivatives including microbial hydration and stereo-specific 1 β-methyl carbapenem synthesis.
2000-10-01