抗糸状菌剤に関する研究 IV : フェニールチオチアネート誘導体の合成ならびに抗菌作用について

概要

論文の詳細を見る
Effects of introduction of Cl, NO_2,NH_2,and SCN radicals to phenylthiocyanate on germination inhibitory activity to conidio spore of Cochliobolus miyabeanus, Alternaria kikuchiana, and bacteriostatic action to Staphylococcus aureus, Escherichia Coli, and Bacterium oryzae were studied. It was found that Cl-introducing compounds had bacteriostatic action, and NO_2-introducing compounds had germination inhibitory activity, furthermore, 2,6-dichloro-4-nitrophenylthiocyanate which were synthesized to have both Cl-and NO_2-radicals exhibited particular antimicrobial activity to both fungi and bacteria. NH_2-introducing compounds of the Cl-derivatives intensified the germination inhibitory activity but reduced the bacteriostatic action.
社団法人日本薬学会の論文
1966-12-30