Biological Monitoring for Chromium Exposures in the Workplace

概要

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The main objective of this study was to assess chromium exposure and to promote understanding of biological monitoring. Workplace activities observed involved production in a leather tannery. The urine Cr and serum Cr level in the specimens of non-occupational controls and occupational workers were determined by graphite furnace atomic absorption spectrophotometry (GFAAS). This technique includes a dilution of serum with 12 mM ultra nitric acid and 1% Triton X-100. The results showed that total serum Cr levels in the exposed occupational workers were significantly higher than those in unexposed non-occupational controls (p<0.05), and that there is a risk of chromium poisoning to the workers engaged in leather tannery worksites. The total urine Cr levels in the exposed workers were no different than in controls (p>0.05). The etiology of chromate poisoning is also briefly mentioned.
公益社団法人日本薬学会の論文
1996-08-31