Screening of the Desmutagenic Capacity of an Extract from Crude Drug by Spore Rec-Assay
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概要
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We investigated the desmutagenic action of extracts from Smilax rhizome, Mulberry bark and Berchemia racemosa on Trp-P-1 and Trp-P-2 by means of spore rec-assay. The results obtained are as follows : (1) 50% ethanol and ethanol extracts from each crude drug showed desmutagenic action on Trp-P-1 and Trp-P-2. (2) Most of the desmutagenic activity in 50% ethanol extract from each crude drug was due to an ethyl acetate soluble fraction. (3) The interaction between the ethyl acetate soluble fraction from each crude drug and Trp-P-1 was much stronger in Mulberry bark and Berchemia racemosa than in Smilax rhizome.
- 公益社団法人日本薬学会の論文
- 2000-02-01
著者
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Ueno Seiichi
Ibaraki Prefectural Hygienic Laboratory
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Ishizaki Mutsuo
Ibaraki Prefectural Hygienic Laboratory
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Ishizaki Mutsuo
Ibaraki Hygienic Laboratory
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Aoki Kazuko
Ibaraki Prefectural Hygienic Laboratory
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