Adsorption Studies of Artesunate : Evaluation of Saline Cathartics as Additive in Management of Artesunate Poisoning
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概要
- 論文の詳細を見る
The effect of saline cathartics magnesium sulphate, sodium sulphate, and sodium citrate on adsorptive capacity of activated charcoal (AC) was investigated in vitro. Solutions of artesunate alone and artesunate with 7.5 mg/ml cathartics solution were vortex mixed for 30 sec with different quantities of AC, incubated in water bath shaker for 30 min at 37℃ and analysed for free artesunate spectrophotometrically at 328 nm. Addition of the cathartics caused a significant increase (p<0.05) in the adsorption of artesunate to activated charcoal. The descending order of increased adsorption by the cathartics is magnesium sulphate, sodium citrate and sodium sulphate.
- 公益社団法人日本薬学会の論文
- 2001-10-01
著者
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Ofoefule Sabinus
Department of Pharmaceutical Technology and Industrial Pharmacy, University of Nigeria
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Afonne Onyenmechi
Toxicology Unit Department Of Pharmacology Nnamdi Azikiwe University Nnewi Campus
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Orisakwe O
Toxicology Unit Department Of Pharmacology Nnamdi Azikiwe University Nnewi Campus
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Afonne Onyenmechi
Departments Of Pharmacology College Of Health Sciences Nnamdi Azikiwe University Nnewi Campus
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Agbasi Patrick
Departments of Pharmacology, College of Health Sciences, Nnamdi Azikiwe University, Nnewi Campus
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Ilondu Ndidi
Departments of Pharmacology, College of Health Sciences, Nnamdi Azikiwe University, Nnewi Campus
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Orisakwe Orish
Toxicology Unit, Department of Pharmacology, College of Health Sciences, Nnamdi Azikiwe University,
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Oluboyo Adeola
Toxicology Unit, Department of Pharmacology, College of Health Sciences, Nnamdi Azikiwe University,
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Obi Ejeatuluchukwu
Toxicology Unit, Department of Pharmacology, College of Health Sciences, Nnamdi Azikiwe University,
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Ilondu Ndidi
Toxicology Unit, Department of Pharmacology, College of Health Sciences, Nnamdi Azikiwe University,
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Agbasi Patrick
Toxicology Unit, Department of Pharmacology, College of Health Sciences, Nnamdi Azikiwe University,
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Chiroma Danladi
Toxicology Unit, Department of Pharmacology, College of Health Sciences, Nnamdi Azikiwe University,
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Chiroma Danladi
Toxicology Unit Department Of Pharmacology College Of Health Sciences Nnamdi Azikiwe University Nnew
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Ilondu N
Departments Of Pharmacology College Of Health Sciences Nnamdi Azikiwe University Nnewi Campus
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Agbasi Patrick
Departments Of Pharmacology College Of Health Sciences Nnamdi Azikiwe University Nnewi Campus
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Oluboyo Adeola
Toxicology Unit Department Of Pharmacology College Of Health Sciences Nnamdi Azikiwe University Nnew
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Agbasu Patrick
Biokinetic Research Group Toxicology Unit Deparment Of Pharmacology College Of Health Science Nnamdi
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Ofoefule S
Department Of Pharmaceutical Technology Faculty Of Pharmacy University Of Nigeria
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Ofoefule Sabinus
Department Of Pharm. Technology & Industrial Pharmacy University Of Nigeria
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Obi Ejeatuluchukwu
Toxicology Unit Department Of Pharmacology Nnamdi Azikiwe University Nnewi Campus
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