Atherosclerosis and Molecular Pathology : Mechanisms of Cholesteryl Ester Accumulation in Foam Cells and Extracellular Space of Atherosclerotic Lesions
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概要
- 論文の詳細を見る
This article reviews aspects of the molecular pathology of cholesteryl ester accumulation in atherosclerotic lesions. 1. Transcytosis of lipoproteins through cultured endothelial monolayer. 2. Transformation to foam cell from macrophage. 3. Cholesteryl ester deposition in the extracellular space of atherosclerotic lesions. We also discuss the development and use of novel monoclonal antibodies recognizing atherosclerotic lesions and peroxidized lipoproteins prepared from atherosclerotic lesions.
- 公益社団法人日本薬学会の論文
著者
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Takano Tatsuya
Department Of Microbiology And Molecular Pathology Faculty Of Phamaceutical Sciences Teikyo Universi
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Mineo C
Teikyo Univ. Kanagawa Jpn
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Mineo Chieko
Department Of Microbiology And Molecular Pathology Faculty Of Pharmaceutical Sciences Teikyo Univers
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Takano Tatsuya
Department Of Microbiology And Molecular Pathology Faculty Of Pharmaceutical Sciences Teikyo Univers
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- Oxidized Low Density Lipoprotein : The Occurrence and Metabolism in Circulation and in Foam Cells
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- Atherosclerosis and Molecular Pathology : Mechanisms of Cholesteryl Ester Accumulation in Foam Cells and Extracellular Space of Atherosclerotic Lesions
- Metabolism of Oxidized Phosphatidylcholines Formed in Oxidized Low Density Lipoprotein by Lecithin-Cholesterol Acyltransferase.