Corneal Permeability to Bunazosin in Rabbits

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概要

• 論文の詳細を見る

• Topical and systemic absorption of bunazosin after topical instillation was investigated in rabbits. Corneal permeability of bunazosin in vivo was increased by the addition of caprylic acid in amounts equimolar to bunazosin. Aqueous humor levels of bunazosin were significantly elevated. These results correlated well with those obtained in vitro experiments. Contrarily, the levels of plasma were not significantly affected and only slightly lowered by caprylic acid.

• 公益社団法人日本薬学会の論文

著者

• Iwata Shuzo

  Department Of Biophysical Chemistry Faculty Of Pharmaceutical Sciences Meijo University

• KATO Akira

  Tsukuba Research Laboratories, Eisai Co., Ltd.

• Kato Akira

  Tsukuba Research Laboratories Eisai Co. Ltd.

関連論文

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• IN VITRO SUBACUTE CATARACTOGENIC STUDY IN RAINBOW TROUT LENS
• Studies on Improved Corneal Permeability to Bunazosin
• Corneal Permeability to Bunazosin in Rabbits
• EVALUATION ON EFFECTS OF ANTI-CATARACT AGENTS : ESPECIALLY ON THE PROBE IN VITRO
• In Vitro Study on Corneal Permeability to Bunazosin

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