Structures of 4-Aryl-coumarin (Neoflavone) Dimers Isolated from Pistacia chinensis BUNGE and Their Estrogen-like Activity
スポンサーリンク
概要
- 論文の詳細を見る
Activity-guided fractionation of twigs of Pistacia chinensis resulted in the isolation and characterization of two novel ingredients as potent estrogen agonists. On the basis of spectral analysis and comparison with a related compound their structures were elucidated as 3,3"-dimers of 4-aryldihydrocoumarins (3,4-dihydro-4-(4'-hydroxyphenyl)-7-hydroxycoumarin) differing only in the stereochemical disposition of the linkage between the two 4-arylcoumarin moieties. These compounds are the first examples of bis-flavonoids which have been proven to possess estrogen-like activity.
- 公益社団法人日本薬学会の論文
- 2000-04-01
著者
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AKIYAMA Toshihiko
Faculty of Pharmaceutical Sciences, Okayama University
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Akimura T
Department Of Neurosurgery Yamaguchi University School Of Medicine
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Akiyama T
Faculty Of Pharmaceutical Sciences Okayama University
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Nishimura S
Exploratory Chemistry Research Laboratories Sankyo Co. Ltd.
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TAKI Motohiko
Pharmacology and Molecular Biology Research Laboratories, Sankyo Co., Ltd.,
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TAKAISHI Sachiko
Pharmacology and Molecular Biology Research Laboratories, Sankyo Co., Ltd.,
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AKIYAMA Toshiyuki
Exploratory Chemistry Research Laboratories, Sankyo Co., Ltd.,
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Taki M
Pharmacology And Molecular Biology Research Laboratories Sankyo Co. Ltd.
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Iijima Y
Pharmacology And Molecular Biology Research Laboratories Sankyo Co. Ltd.
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Iijima Yasuteru
Pharmacology And Molecular Biology Research Laboratories Sankyo Co. Ltd.
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NISHIMUTA Satoshi
Exploratory Chemistry Research Laboratories, Sankyo Co., Ltd.,
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Takaishi S
Pharmacology And Molecular Biology Research Laboratories Sankyo Co. Ltd.
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Nishimura Satoshi
Exploratory Chemistry Research Laboratories, Sankyo Co., Ltd.,
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