2-Hydroxy-5-(ethanolamino)-3-(10'-Z-pentadecenyl)-1,4-benzoquinone, New Microbial Phase II Metabolite of Maesanin

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概要

• 論文の詳細を見る

• The use of microbial models for biotransformation of the natural benzoquinone, maesanin (1), resulted in the isolation of an ethanolamine conjugate (5) from the culture broth of Debaryomyces polymorphus ATCC 20280. Metabolite 5 was characterized as 2-hydroxy-5-(ethanolamino)-3-(10'-Z-pentadecenyl)-1,4-benzoquinone. The production of 5 represents a new type of phase II conjugation reaction in microbial systems. The results of preliminary mammalian metabolism of 1 in rats were incondlusive.

• 公益社団法人日本薬学会の論文
• 2000-01-01

著者

• Khan Ikhlas

  Department Of Pharmacognosy And National Center For Natural Products Research Research Institute Of

• Abourashed Ehab

  Department Of Pharmacognosy And National Center For Natural Products Research Research Institute Of

• El-feraly Farouk

  Department Of Pharmacognosy College Of Pharmacy King Saud University

• HUFFORD Charles

  Department of Pharmacognosy and National Center for Natural Products Research, Research Institute of

• Hufford Charles

  Department Of Pharmacognosy And National Center For Natural Products Research Research Institute Of

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• 2-Hydroxy-5-(ethanolamino)-3-(10'-Z-pentadecenyl)-1,4-benzoquinone, New Microbial Phase II Metabolite of Maesanin

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