Effect of Biotin on Biochemical Changes following Isoproterenol-induced Myocardial Infarction in Rats
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概要
- 論文の詳細を見る
Effect of biotin on biochemical changes following isoproterenol-induced myocardial infarction in rats was investigated. Biotin inhibited an increase of myocardial water content, an elevation of plasma lactate dehydrogenase activity and a decrease of myocardial adenosine triphosphate (ATP) level in isoproterenol-treated rats. Prednisolone enhanced the inhibitory effects of biotin on myocardial water content and plasma lactate dehydrogenase activity, but did not influence on myocardial ATP level. A possible mechanism of the inhibition by biotin is discussed.
- 公益社団法人日本薬学会の論文
- 1976-06-25
著者
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吉田 耕一
大日本製薬株式会社総合研究所
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清水 当尚
Research and Development Division, Dainippon Pharmaceutical Co., Ltd.
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坪井 俊紀
Research Laboratory, Dainippon Pharmaceutical Co., Ltd.
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吉田 耕一
Research Laboratory, Dainippon Pharmaceutical Co., Ltd.
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清水 当尚
大日本製薬株式会社 総合研究所
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清水 当尚
Research And Development Division Dainippon Pharmaceutical Co. Ltd.
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藤谷 武一
大日本製薬総研
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藤谷 武一
Research Laboratory, Dainippon Pharmaceutical Co., Ltd.
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武野 一子
Research Laboratory, Dainippon Pharmaceutical Co., Ltd.
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坪井 俊紀
大日本製薬総研
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武野 一子
Research Laboratory Dainippon Pharmaceutical Co. Ltd.
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