LEWIS ACID CATALYZED DIELS-ALDER REACTION OF 3-PHENYLTHIO-2-QUINOLINONES WITH SILOXYDIENE. SYNTHESIS OF THE INTERMEDIATE FOR DYNEMICIN A CORE

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概要

• 論文の詳細を見る

• Preparation of the 1-methoxycarbonyl-3-phenylthio-2-quinolinone (10) from dihydro-2-quinolinone (5) and its Diels-Alder reaction with 2-trimethylsilyloxy-1,3-butadiene under Lewis acid catalyst is described. Conversion of the D-A adduct (11) to 9-phenenthridinone ketal (16) will open a new synthetic route to a dynemicin A core structure.

• 公益社団法人日本薬学会の論文
• 1996-02-15

著者

• Hino Tohru

  Faculty Of Pharmaceutiical Sciences Chiba University

• Hino Tohru

  Faculty Of Pharmaceutical Sciences Chiba University

• Koide Y

  Faculty Of Pharmaceutical Sciences Chiba University

• Nagata Toshiaki

  Faculty Of Pharmaceutical Sciences Chiba University

• Nakagawa Masako

  Faculty of Pharmaceutical Sciences, Chiba University

• KOIDE Yuuki

  Faculty of Pharmaceutical Sciences, Chiba University

• NARA Kazumasa

  Faculty of Pharmaceutical Sciences, Chiba University

• ITOH Etsuko

  Faculty of Pharmaceutical Sciences, Chiba University

• ARISAWA Mitsuhiro

  Faculty of Pharmaceutical Sciences, Chiba University

• NARUTO Shunji

  Neuroscience Research Laboratories, Sankyo Co. LTD.,

• TORISAWA Yasuhiro

  Faculty of Pharmaceutical Sciences, Chiba University

• Itoh Etsuko

  Faculty Of Pharmaceutical Sciences Chiba University

• Nara Kazumasa

  Faculty Of Pharmaceutical Sciences Chiba University

• Nakagawa M

  Faculty Of Pharmaceutical Sciences Chiba University

• Nakagawa Masako

  Graduate School Of Pharmaceutical Sciences Chiba University

• Nakagawa Masako

  Faculty Of Medicine Mie University

• Torisawa Yasuhiro

  Faculty Of Pharmaceutical Sciences Chiba University

• Arisawa M

  Faculty Of Pharmaceutical Sciences Chiba University

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• LEWIS ACID CATALYZED DIELS-ALDER REACTION OF 3-PHENYLTHIO-2-QUINOLINONES WITH SILOXYDIENE. SYNTHESIS OF THE INTERMEDIATE FOR DYNEMICIN A CORE
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