Enantioselective Distribution of Amino-Alcohols in a Liquid-Liquid Two-Phase System Containing Dialkyl L-Tartrate and Boric acid
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概要
- 論文の詳細を見る
Racemic amino-alcohols such as pindolol, propranolol, alprenolol and bucumolol enantiomers exhibited different distribution behaviors in a two-phase system consisting of a chloroform solution of didodecyl L-tartrate and an aqueous solution of boric acid. It seemed that a borate complex of the 1,2-diol group of the tartrate and the amino-alcohol was formed in the system. In the case of pindolol, one enantiomer was preferentially extracted into the organic phase (×2.20) at equilibrium.
- 公益社団法人日本薬学会の論文
- 1995-02-15
著者
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阿部 芳廣
共立薬科大学
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阿部 芳広
共立薬大
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Shoji T
Kyoritsu College Of Pharmacy
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庄子 知子
Kyoritsu College Of Pharmacy
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Shoji Tomoko
Kyoritsu College Of Pharmacy
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Asai N
Kyoritsu College Of Pharmacy
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浅井 直子
Kyoritsu College Of Pharmacy
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阿部 芳廣
Kyoritsu College of Pharmacy
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小林 美智
Kyoritsu College of Pharmacy
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王 菁
Kyoritsu College of Pharmacy
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西澤 秀幸
Kyoritsu College of Pharmacy
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王 菁
Kyoritsu Coll. Pharmacy Tokyo Jpn
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