Synthesis of Thromboxane B_3 and Its Direct Separation from Thromboxane B_2 by Reversed-Phase High Performance Liquid Chromatography

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概要

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• The first chemical synthesis of thromboxane B_3 starting with the Corey lactone is described. A reversed-phase high-performance liquid chromatographic method was developed for the direct determination without derivatization, of thromboxane B_3 in the presence of thromboxane B_2.

• 公益社団法人日本薬学会の論文
• 1993-10-15

著者

• 永井 寛子

  Minase Research Institute Ono Pharmaceutical Co. Ltd.

• 井口 貞彦

  Minase Research Institute, Ono Pharmaceutical Co., Ltd.,

• 川村 雅範

  Minase Research Institute, Ono Pharmaceutical Co., Ltd.,

• 中村 信之

  Minase Research Institute, Ono Pharmaceutical Co., Ltd.,

• 米田 真紀子

  Minase Research Institute, Ono Pharmaceutical Co., Ltd.,

• 須賀 久

  Minase Research Institute, Ono Pharmaceutical Co., Ltd.,

• 川村 雅範

  Minase Research Institute Ono Pharmaceutical Co. Ltd.

• 須賀 久

  Minase Research Institute Ono Pharmaceutical Co. Ltd.

• 井口 貞彦

  Minase Research Institute Ono Pharmaceutical Co. Ltd.

• 米田 真紀子

  Minase Research Institute Ono Pharmaceutical Co. Ltd.

• 中村 信之

  Minase Research Institute Ono Pharmaceutical Co. Ltd.

関連論文

• Synthesis of 15-cis-(4-n-Propylcyclohexyl)-16,17,18,19,20-pentanor-9-deoxy-6,9α-nitriloprostaglandin F_1 Methyl Ester (OP-2507), a Novel Anti-cerebral Ischemic Agent
• Development of a Highly Cardioselective Ultra Short-Acting β-Blocker, ONO-1101
• Synthesis of Thromboxane B_3 and Its Direct Separation from Thromboxane B_2 by Reversed-Phase High Performance Liquid Chromatography

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