Presence of the Basement Membrane Component-Heparan Sulfate Proteoglycan-in Bovine Lens Capsules

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概要

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• Heparan sulfate proteoglycan was extracted from bovine lens capsules by 0.45 M NaCl/2 M urea and purified using ion-exchange chromatography and gel filtration. The proteoglycan was found to consist of protein and carbohydrate in a ratio of 75 to 25. The estimated average molecular weight of the heparan sulfate proteoglycan eluted by 0.2 M NaCl on a diethylaminoethyl (DEAE)-cellulose column was 400 kilodaltons (kDa) and that of its glycosaminoglycan was 18.8 kDa. The amino acid composition of the proteoglycan was quite similar to that of the bovine glomelular basement membrane.

• 公益社団法人日本薬学会の論文
• 1991-04-25

著者

• 小野寺 敏

  Department of Clinical and Biomedical Sciences, Showa Pharmaceutical University

• 小野寺 敏

  Department Of Clinical Chemistry Showa College Of Pharmaceutical Sciences

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