Proton Nuclear Magnetic Relaxation : An Application to the Study of the Conformation and Configuration of Saframycin A
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概要
- 論文の詳細を見る
Proton nuclear magnetic resonance (^1H-NMR) relaxation of saframycin A in C_6D_6 has been studied. Quantitative analysis of spin-lattice relaxation times and nuclear Overhauser effect (NOE) factors allowed the determination of the α-axial orientation of the nitrile group at C_<21>, (previously unknown). The conformation of saframycin A in C_6D_6,which was deduced from the relaxation data, was compared with that of saframycin C in the crystal state.
- 公益社団法人日本薬学会の論文
- 1985-03-25
著者
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春山 英幸
Analytical and Metabolic Research Laboratories
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近藤 三千男
Analytical and Metabolic Research Laboratories, Sankyo Co., Ltd.
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春山 英幸
Analytical And Metabolic Research Laboratories Sankyo Company Ltd.
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栗原 英志
Central Research Laboratories Sankyo Co. Ltd.
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栗原 英志
三共(株)活性物質研究所
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栗原 英志
Sankyo Research Laboratories Sankyo Co. Ltd.
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近藤 三千男
Analytical And Metabolic Research Laboratories Sankyo Company Ltd.
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栗原 英志
Fermentation Research Laboratories, Sankyo Co., Ltd.
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