Antitumor Effect of Oral Cisplatin on Certain Murine Tumors
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概要
- 論文の詳細を見る
The comparative antitumor effects of cisplatin were investigated against several murine tumors after i.p., i.v., and oral administrations. A single administration of cisplatin could significantly inhibit the growth of both L1210 and P388 leukemias, and EL-LP-12 tumors under the conditions used. Oral cisplatin was tested against EL-LP-12 in combination with 6 other antitumor drugs. Cisplatin was inhibitory in binary combination with mitomycin C, vinblastine, 5-fluorouracil, carmustine (BCNU), and cyclophosphamide. In particular, the drug combined with either BCNU or cyclophosphamide showed marked therapeutic synergism.
- 公益社団法人日本薬学会の論文
- 1985-12-25
著者
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長谷川 嘉成
Bristol-myers Research Institute Ltd.
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森田 眞寿行
Bristol-Myers Research Institute, Ltd.
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森田 眞寿行
Bristol-myers Research Institute Ltd.
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