A Convenient Synthesis of Pyridoxine

スポンサーリンク

概要

• 論文の詳細を見る

• A novel and convenient synthesis of pyridoxine starting from N-(1-cyanoethyl) formamide is described. The reaction of N-(1-cyanoethyl) acylamides with olefins in the presence of an acid catalyst gave 3-amino-2-methylpyridines. Similar reaction of N-(1-cyanoethyl) formamide with fumaronitrile in the presence of trifluoroacetic acid afforded 5-amino-6-methylpyridine-3,4-dicarbonitrile, which was easily converted to pyridoxine by reduction and diazotization.

• 公益社団法人日本薬学会の論文
• 1984-01-25

著者

• 嶋田 定勝

  Production Technology Research Laboratories Daiichi Seiyaku Co. Ltd.

• 沖 正信

  Production Technology Research Laboratories, Daiichi Seiyaku Co., Ltd.

• 沖 正信

  Research Laboratories of Production Technology, Daiichi Seiyaku Co., Ltd.

• 沖 正信

  Production Technology Research Laboratories Daiichi Seiyaku Co. Ltd.

関連論文

• Reaction of 1,2,4-Triazines with N-Phenylmaleimide(Organic,Chemical)
• A Convenient Synthesis of Pyridoxine
• Intramolecular Diels-Alder Reaction of Alkenyl Oxazole-5-carbamates and N-Alkenyl-oxazole-5-carboxamides
• A One-Pot Synthesis of 3-Aminopyridines

スポンサーリンク