Biological Fate of Butylated Hydroxytoluene (BHT) : Subcellular Distribution of BHT in Rat Liver

スポンサーリンク

概要

• 論文の詳細を見る

• Biological fate of ^<14>C-labeled butylated hydroxytoluene (^<14>C-BHT) in rat liver was investigated. After a single oral dose of ^<14>C-BHT, the radioactivity was reached a maximum concentration in the liver after 6 hr and in the serum after 6-12 hr. A bulk of radioactivity was found in the supernatant fraction, although the amount of radioactivity and specific radioactivity increased in the microsomal fraction with time. The radioactivity which was incorporated into the microsomal fraction was mainly located in the smooth ER 3-6 hr after the administration. These results suggest that the radioactivity, which was incorporated into the supernatant fraction, migrated to the microsomal fraction.

• 1978-02-25

著者

• 平賀 興吾

  Department Of Toxicology Tokyo Metropolitan Research Laboratory Of Public Health Department Of Clini

• 中川 好男

  Department Of Toxicology Tokyo Metropolitan Research Laboratory Of Public Health Department Of Clini

• 伊川 三枝子

  Department of Toxicology, Tokyo Metropolitan Research Laboratory of Public Health

• 伊川 三枝子

  Department Of Toxicology Tokyo Metropolitan Research Laboratory Of Public Health

関連論文

• Biological Fate of Butylated Hydroxytoluene (BHT) : Binding in Vitro of BHT to Liver Microsomes
• Biological Fate of Butylated Hydroxytoluene (BHT) ; Binding in Vivo of BHT to Macromolecules of Rat Liver
• Inhibition by 3-Amino-1,2,4-triazole of Fatty Acid Synthesis in Cell Free System
• Biological Fate of Butylated Hydroxytoluene (BHT) : Subcellular Distribution of BHT in Rat Liver

スポンサーリンク