Studies on Isothiazoles. I. 3-Arylisothiazole-4-carboxylic Acids

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概要

• 論文の詳細を見る

• Preparations of 5-methyl-3-phenylisothiazole-4-carboxylic acid (Xa) and related compounds are described. 3-(Halogen-substituted phenyl)-5-methylisothiazole-4-carboxylic acids were also obtained by halogenation of 4-cyano-5-methyl-3-phenylisothiazole (VIIa), followed by hydrolysis. 5-Bromo-3-phenylisothiazole-4-carboxylic acid (XV) was prepared, and converted into the 5-methylthio derivative (XVI) which was oxidized to the corresponding sulfoxide (XVII) and sulfone (XVIII).

• 社団法人日本薬学会の論文
• 1968-01-25

著者

• 中川 晋

  Bristol-banyu Research Institute Ltd.

• 内藤 隆之

  Bristol-myers Squibb Research Institute Ltd. Tokyo Research Center

• 内藤 隆之

  Bristol-banyu Research Institute Ltd.

• 高橋 清

  Bristol-Banyu Research Institute, Ltd.

• 高橋 清

  Bristol-banyu Research Institute Ltd.

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• Complete Structures of Breynins A and B
• ネオマイシンBからパロモマイシン1およびその6′′′-OH異性体への化学変換 (糖質の化学)
• Chemical Studies on Breynin A, Breynogenin and Breynolide
• 18 Breynogeninの構造研究
• Studies on Isothiazoles. II. Nitration of 3-Phenylisothiazoles
• Studies on Isothiazoles. I. 3-Arylisothiazole-4-carboxylic Acids
• Studies on Preparation of 3-Hydroxy-4-phenyl-1,2,5-thiadiazole in Various Solvents

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