Studies on A-Norsteroids. III. Hydrogenations of A-Nor-Δ^<3(5)>-steroids Substituted at C_1 and C_2-Positions
スポンサーリンク
概要
- 論文の詳細を見る
Catalytic hydrogenations of the A-nor-Δ^<3(5)>-steroid derivatives have been described. The unsaturated 1β, 2β, 17β-(I) and 1β, 2α, 17β-(II) triols on hydrogenation with palladium-charcoal afforded afforded the saturated 1β, 17β-diol(IIIa) accompanied with hydrogenolysis of their allylic C_2-hydroxyl group, while with Adams' catalyst gave the respective trihydroxy-5β-steroids (IVa) and (VIa). The unsaturated 1β, 17β-dihydroxy-2-one (VIIa) was hydrogenated over palladium-charcoal into the corresponding 5β-steroid (VIIIa), but with Adams' catalyst to yield exclusively the 5α-steroid (XIa).
- 社団法人日本薬学会の論文
- 1965-02-25
著者
-
久保田 徳夫
Shionogi Research Laboratory, Shionogi & Co., Ltd.
-
吉田 圭治
Shionogi Research Laboratory Shionogi & Co. Ltd.
-
久保田 徳夫
Shionogi Research Laboratory Shionogi & Co. Ltd.
関連論文
- The C-1,2 Isomeric Ketols and Diols in 17β-Hydroxy-A-nor-5α-androstane Series
- Syntheses of 1α, 2α-and 1β, 2β-Epithio-A-nor-5α-androstan-17β-ol and Related Compounds.
- The Configuration of the Products obtained from Hydroxylation of Steroidal Δ^-3-Ketones with Osmium Tetroxide
- Studies on A-Norsteroids. I. Synthesis of A-Nor-Δ^-1,2-dioxo Steroids
- Studies on A-Norsteroids. V. Reaction of Steroidal Diosphenols with Manganese Dioxide
- Studies on A-Norsteroids. III. Hydrogenations of A-Nor-Δ^-steroids Substituted at C_1 and C_2-Positions
- Studies on A-Norsteroids. II. Reactions of 17β-Hydroxy-A-norandrost-3(5)-ene-1,2-dione with Several Reagents
- Bile Acids and Steroids. X. On β-Spinasterol.
- Bile Acids and Steroids. XIII. Thiosteroids. (2). Addition of Thiocyanic Acid to Steroidal α, β-Unsaturated Ketones
- Studies on the Steroidal Components of Domestic Plants. XVIII. Components of the Root of Bupleurum falcatum L. (2).
- Studies on Seven-membered Ring Derivatives. III. : Partial Synthesis of 1,4-Dimethyl-7-ethylazulene (Lindazulene).
- Studies on the Steroidal Components of Domestic Plants. XX. The Structure of Kogagenin. (2)