Studies on A-Norsteroids. II. Reactions of 17β-Hydroxy-A-norandrost-3(5)-ene-1,2-dione with Several Reagents
スポンサーリンク
概要
- 論文の詳細を見る
Reactions of 17β-hydroxy-A-norandrost-3(5)-ene-1,2-dione (Ia) and its 17-propionate (Ib) with several reagents have been examined. Treatment of I with zinc-acetic acid or lithium-liquid ammonia resulted in the reduction of only the C_1-carbonyl group giving 1β, 17β-dihydroxy-A-norandrost-3(5)-en-2-one (II). On the contrary, reaction of I with carbonyl reagents in the usual condition afforded the corresponding derivatives which were condensed at only the C_2-carbonyl group with the reagents. Lithium aluminum hydride or sodium borohydride reduction of I gave the glycols, (IV) and (V), epimeric at C-2 with the 1β-hydroxyl group.
- 社団法人日本薬学会の論文
- 1965-02-25
著者
-
久保田 徳夫
Shionogi Research Laboratory, Shionogi & Co., Ltd.
-
吉田 圭治
Shionogi Research Laboratory Shionogi & Co. Ltd.
-
久保田 徳夫
Shionogi Research Laboratory Shionogi & Co. Ltd.
関連論文
- The C-1,2 Isomeric Ketols and Diols in 17β-Hydroxy-A-nor-5α-androstane Series
- Syntheses of 1α, 2α-and 1β, 2β-Epithio-A-nor-5α-androstan-17β-ol and Related Compounds.
- The Configuration of the Products obtained from Hydroxylation of Steroidal Δ^-3-Ketones with Osmium Tetroxide
- Studies on A-Norsteroids. I. Synthesis of A-Nor-Δ^-1,2-dioxo Steroids
- Studies on A-Norsteroids. V. Reaction of Steroidal Diosphenols with Manganese Dioxide
- Studies on A-Norsteroids. III. Hydrogenations of A-Nor-Δ^-steroids Substituted at C_1 and C_2-Positions
- Studies on A-Norsteroids. II. Reactions of 17β-Hydroxy-A-norandrost-3(5)-ene-1,2-dione with Several Reagents
- Bile Acids and Steroids. X. On β-Spinasterol.
- Bile Acids and Steroids. XIII. Thiosteroids. (2). Addition of Thiocyanic Acid to Steroidal α, β-Unsaturated Ketones
- Studies on the Steroidal Components of Domestic Plants. XVIII. Components of the Root of Bupleurum falcatum L. (2).
- Studies on Seven-membered Ring Derivatives. III. : Partial Synthesis of 1,4-Dimethyl-7-ethylazulene (Lindazulene).
- Studies on the Steroidal Components of Domestic Plants. XX. The Structure of Kogagenin. (2)