Studies on Carcinostatic Substances. XXXIII. Preparation of Derivatives of Nitrogen Mustard of Strongly Basic Character.

スポンサーリンク

概要

• 論文の詳細を見る

• Derivatives of N, N-dialkyl-N', N'-bis (2-chloroethyl) polymethylenediamine and some of their N, N'-dioxides were synthesized. These compounds are supposed to remain as cations even in physiological liquids contrary to N-methyl-bis (2-chloroethyl) amine, because the dialkylamino group in these molecules is far more strongly basic than bis (2-chloroethyl)-amino group. Relationship between anti-tumor activity and chemical and physical characteristics of these compounds are also discussed.

• 公益社団法人日本薬学会の論文
• 1961-05-25

著者

• 愛甲 軍雄

  Yoshitomi Pharmaceutical Industries Ltd.

関連論文

• On the Optical Isomers of α-[N-Bis (β-chloroethyl) amino] propionamide.
• Polarographic Determination of Half-wave Potentials of Nitrogen Mustard N-Oxides
• Studies on Carcinostatic Substances. XXX. Syntheses of Derivatives of Nitrogen Mustard related to Amino Acid.
• Studies on Carcinostatic Substances. XXVI. Preparation of Bis(2-chloroethyl)amine Derivatives and Related N-Oxides.
• Studies on Carcinostatic Substances. XXXIII. Preparation of Derivatives of Nitrogen Mustard of Strongly Basic Character.

スポンサーリンク