Studies on Carcinostatic Substances. XXXVIII. Chemical and Antitumor Properties of Monofunctional Derivatives of Nitrogen Mustard.
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Supported by the fact that N-methyl-N-2-chloroethyl-3-chloropropylamine exhibited a strong antitumor effect on Yoshida sarcoma or series of rat ascites hepatomas, eight derivatives of nitrogen mustard were newly synthesized, which have only one but highly reactive 2-chloroethyl group in a molecule. Antitumor test of these compounds on Yoshida sarcoma was, however, negative.
- 公益社団法人日本薬学会の論文
- 1961-12-25
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関連論文
- Studies on Carcinostatic Substances. XXXVII. Preparation of Derivatives of Nitrogen Mustard having Metal Chelate-forming Activity.
- Studies on Carcinostatic Substances. XXXIX. Antitumor Effect of Derivatives of Nitrogen Mustard containing only one 2-Chloroethyl Group.
- Studies on Carcinostatic Substances. XXXVIII. Chemical and Antitumor Properties of Monofunctional Derivatives of Nitrogen Mustard.