Facile Synthesis of 3-Methoxy-10,11-dihydro-5H-dibenzo[a, d]cyclohepten-5-one : Application to the Acid-Labile Peptide Amide Linker Containing the 10,11-Dihydro-5H-dibenzo[a, d]cycloheptene Moiety

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概要

• 論文の詳細を見る

• The facile synthesis of 3-methoxy-10,11-dihydro-5H-dibenzo[a, d]cyclohepten-5-one (5) via m-methoxystilbene-2-carboxylic acid (3) was developed for the preparation of the mild acid labile peptide amide linker containing 10,11-dihydro-5H-dibenzo[a, d]cyclohepten-5-yl group for Fmoc (9-Fluorenylmethoxycarbonyl)-solid phase peptide synthesis.

• 公益社団法人日本薬学会の論文
• 1998-07-15

著者

• Noda M

  Shimadzu Corp. Kyoto Jpn

• Noda Masaki

  Technology Research Laboratory Shimadzu Corp.

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• A Highly Stereoselective Synthesis of The Functionalized (E)-Alkene Dipeptide Isostere of Trp-Val via Organocyanocopper-Lewis Acid Mediated Reaction
• Facile Synthesis of 3-Methoxy-10,11-dihydro-5H-dibenzo[a, d]cyclohepten-5-one : Application to the Acid-Labile Peptide Amide Linker Containing the 10,11-Dihydro-5H-dibenzo[a, d]cycloheptene Moiety
• Thermal Catalytic Depolymerization of Poly(L-Lactic Acid) Oligomer into LL-Lactide : Effects of Al, Ti, Zn and Zr Compounds as Catalysts

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