Synthesis and Antimicrobial Activity of N-(Substituted)-N'-(2,3-dihydro-2-oxido-5-benzoyl-1H-1,3,2-benzodiazaphosphol-2-yl) Ureas

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概要

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• N-(Substituted)-N'-(2,3-dihydro-5-benzoyl-2-oxido-1H-1,3,2-benzodiazaphosphol-2-yl) ureas were synthesized by reacting 3,4-diaminobenzophenone (4) with different chlorides of carbamidophosphoric acids (3) in the presence of triethylamine at 40-45℃. Their ^1H-, ^<13>C- and ^<31>P-NMR spectral data are discussed. The title compounds were screened for antifungal and antibacterial activity against the fungi Aspergillus niger and Fusarium solani and bacteria Escherichia coli and Staphylococcus aureus. These compounds showed higher antibacterial activity when compared with antifungal activity.

• 公益社団法人日本薬学会の論文
• 2003-07-01

著者

• Suresh Reddy

  Department Of Chemistry Biochemistry S.v. University

• Suresh Reddy

  Department Of Chemistry Sri Venkateswara University College Of Engineering

• Vasu Govardhana

  Department Of Chemistry Sri Venkateswara University College Of Engineering

• Naga Raju

  Department Of Chemistry Sri Venkateswara University College Of Engineering

関連論文

• One-Step Synthesis and Bioassay of N-Phosphoramidophosphonates
• Synthesis, Anti-bacterial and Anti-oxidant Properties of Thiadiazaphosphol-2-ones
• Synthesis and Antimicrobial Activity of Novel Phosphorus Heterocycles with Exocyclic P-C Link
• Synthesis and Antimicrobial Activity of N-(Substituted)-N'-(2,3-dihydro-2-oxido-5-benzoyl-1H-1,3,2-benzodiazaphosphol-2-yl) Ureas

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