Reducing Activity of Colloidal Platinum Nanoparticles for Hydrogen Peroxide, 2,2-Diphenyl-1-picrylhydrazyl Radical and 2,6-Dichlorophenol Indophenol (Medicinal Chemistry)
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概要
- 論文の詳細を見る
Shimizu and Tsuji established a method of preparing colloidal platinum nanoparticles, whose average size is 2 nm, by ethanol reduction of H_2PtCl_6 in the absence of protective agents for the particles. Platinum nanoparticles have negative surface potential and are stably suspended from an electric repulsion between them. The platinum nanoparticles reduced hydrogen peroxide and 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) below 0.1 ppm. It is necessary to use higher concentration of platinum nanoparticles for the reduction of 2,6-dichlorophenol indophenol (DCIP) than that of hydrogen peroxide and 2,2-diphenyl-1-picrylhydrazyl radical, because reoxidation of DCIPH_2 (reduced) by oxygen was not negligible under our experimental conditions. These results indicate that electrons on platinum nanoparticles produced by the method of Shimizu and Tsuji can reduce hydrogen peroxide, DPPH radical or DCIP transferring electrons.
- 2004-05-01
著者
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NAKAJO Shigeo
Laboratory of Biochemistry, Yokohama College of Pharmacy
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NAKAYA Kazuyasu
Animal Cell Biological Engineering, Niigata University of Pharmacy and Applied Life Science
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Nakajo S
Laboratory Of Biochemistry Yokohama College Of Pharmacy
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Nakaya K
Animal Cell Biological Engineering Niigata University Of Pharmacy And Applied Life Science
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Nakaya Kazuyasu
School Of Pharmaceutical Sciences Showa University
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Nakaya Kazuyasu
Laboratory Of Biological Chemistry School Of Pharmaceutical Science Showa University
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Nakaya Kazuyasu
Animal Cell Biological Engineering Niigata University Of Pharmacy And Applied Life Science
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Aiuchi T
Laboratory Of Biological Chemistry School Of Pharmaceutical Sciences Showa University
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AIUCHI Toshihiro
Laboratory of Biological Chemistry, School of Pharmaceutical Sciences, Showa University
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