Studies on the Antioxidant Activities of Desmodium gangeticum(Pharmacognosy)
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概要
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Desmodium gangeticum is herbal species which is widely used in the indigenous system of medicine and is reported to contain flavone and isoflavanoid glycosides. In view of its wide use and it's chemical composition, this study was aimed at examining the antioxidant activity of the extract of D. gangeticum. The extract was studied for diphenyl picryl hydrazyl (DPPH), nitric oxide, ferryl-bipyridyl and hypochlorous acid scavenging activity along with lipid peroxidation. Nitric oxide was generated using sodium nitroprusside and was studied using Griess reagent. In order to study the iron chelating capacity of the extract, the percentage ferryl-bipyridyl inhibition was studied. Hypochlorous acid scavenging activity was tested by measuring the inhibition of 5-thio-2-ni-trobenzoic acid oxidation. The extract was also studied for lipid peroxidation assay by thiobarbituric acid-reactive substances (TBARS) method using rat brain homogenate. The results indicate that D. gangeticum extract has potent antioxidant activity.
- 2003-10-01
著者
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Rawat Ajay
Pharmacognosy And Ethnopharmacology Division National Botanical Research Institute
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Govindarajan Raghavan
Pharmacognosy And Ethnopharmacology Division National Botanical Research Institute
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Vijayakumar Madhavan
Pharmacognosy And Ethnopharmacology Division National Botanical Research Institute
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Mehrotra Shanta
Pharmacognosy And Ethnopharmacology Division National Botanical Research Institute
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SHIRWAIKAR Annie
Pharmacognosy Department, College of Pharmaceutical Sciences
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PUSHPANGADAN Palpu
Pharmacognosy and Ethnopharmacology Division, National Botanical Research Institute
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RASTOGI Subha
Pharmacognosy and Ethnopharmacology Division, National Botanical Research Institute
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Rastogi Subha
Pharmacognosy And Ethnopharmacology Division National Botanical Research Institute
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Shirwaikar Annie
Dep. Of Pharmacognosy Manipal Coll. Of Pharmaceutical Sciences
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Pushpangadan Palpu
Pharmacognosy And Ethnopharmacology Division National Botanical Research Institute
関連論文
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