^<99m>Tc-DTPAを使用した糸球体濾過値(GFR)および腎血漿流量(RPF)同時測定とその臨床的意義

概要

論文の詳細を見る
We tried a method to briefly measure GFR and RPF simultaneously with the production of renal RI angiogram and renogram using ^<99m>Tc-DTPA. For the GFR measurement, we instituted ROI on a bladder part after finishing renogram, and made computations by the half-hourly bladder excretion rate and coefficient Kl. For the RPF measurement, we found that the first phase of ^<99m>Tc-DTPA renogram curve was in proportion to renal blood flow and computed the RPF measurement from this maximum count, blood count and coefficient K2. Both the coefficients K1 and K2 were computed from ^<99m>Tc-DTPA clearance and ^<131>I-Hippuran clearance by urine collection. We compared GFR (68 cases) and RPF (33 cases) which compute by the method mentioned above with the creatinine clearce and PAH clearace. GFR : Correlation coefficient (0.926) Linear regression Y=0.785X+8.533 RPF : Correlation coefficient (0.802) Linear regression Y=0.869X+45.24 In this way, we got very good correlation. Judging from the foregoing observations, we concluded that the results obtained by this method were well reflected in the function and can be taken as a standard for knowing the renal function, and further, this not being influenced by the urination impediment etc. is a clinically useful method for quantitative renal function examination.
社団法人日本放射線技術学会の論文
1984-01-01