Properties of the unc-52 Gene and Its Related Mutations in the Nematode Caenorhabditis elegans(Genetics)
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概要
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The mutations in the unc-52 gene show a stage-dependent uncoordinated (Unc) phenotype and belong to either severely or mildly paralyzed Unc (Brenner, 1974; Mackenzie et al., 1978; Zengel and Epstein, 1980; Hosono et al., 1981). One recessive allele (cn10) of the unc-52 gene, belonging to one of the most severely paralyzed group, and its revertants are depicted. Isolated as a revertant of the severe type allele, unc-52 (cn10) cnDp1 (f) produces two types of progeny ; parental severe-type and recovered mild-type Unc. Genetic evidence is presented showing that the property of cnDp1 is brought about by the presence (i.e., mild type) or absence (i.e., severe type) of the free chromosomal fragment containing the unc-52 (cn10) gene. Based on the properties of the strain containing cn Dp1 (f), the role of the unc-52 gene is discussed.
- 社団法人日本動物学会の論文
- 1985-02-15
著者
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Hosono Ryuji
Department Of Biochemistry School Of Medicine Kanazawa University
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KUNO SIGERU
Department of Biochemistry, School of Medicine, Kanazawa University
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Kuno Sigeru
Department Of Biochemistry School Of Medicine Kanazawa University
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